The idea of quality of life has developed into a core idea in both theoretical and practical research to the point where it is now used as a key framework for developing and evaluating supports and services. For persons with disabilities and their families, it also serves as a theoretical research model, a guideline for creating evidence-based practices, and a way to put into practice and redefine professional practices.The study set out to explore the efficacy of interventions to improve the Quality of Life (QOL) for Children with Autism (CWA) and their families. The study aimed to examine in depth parents’ perspectives (past and present experiences) and expectations (on future) towards raising their children with autism; and effectiveness of interventions towards improving the QOL of CWA and their families. A systematic review of the literature was done to locate pertinent information and locate various literature to support the QoL of CWA.The study was guided by the theory of Social Constructivism by Vygotsky in 1978.The research criteria was met by a total of 39 papers, which were then reviewed. Research gate, EBSCO, ERIC , google scholar, social services abstracts were used in an electronic database search.In comparison to parents of usually developing children or to the general community, this review found that parents of children with ASD had lower quality of life. Child behavioural issues, unemployment, being a woman, and a lack of social support were all factors linked to lower parental quality of life in this group. The study's findings further show that contextual intervention significantly increased children's engagement in activities that parents found valuable, and that working together to develop strategies for achieving goals makes parents feel more capable in their parenting roles.In comparison to adults who were not parents of children with ASD, it was discovered that QOL was lower among parents of children with ASD in terms of physical, psychological, social, and spiritual wellbeing. The greatest risk for parental QOL was the severity of the diagnosis of ASD. Education levels of the parents and the child's ASD severity levels were protective factors for parental QOL.