Trans-eQTL effects on risk of type 1 diabetes: a test of the sparse effector (omnigenic) hypothesis of complex trait genetics (supplementary data)

Authors: Iakovliev, Andrii; McGurnaghan, Stuart; Hayward, Caroline; Colombo, Marco; Lipschutz, Debby; Spiliopoulou, Athina; Colhoun, Helen M; +1 Authors

doi: 10.5281/zenodo.7786861 , 10.5281/zenodo.7786862

Trans-eQTL effects on risk of type 1 diabetes: a test of the sparse effector (omnigenic) hypothesis of complex trait genetics (supplementary data)

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Abstract

This study was supported by Diabetes UK [15/0005301]. The establishment of the SDRN Type 1 Bioresource was supported by the Chief Scientist Office of the Scottish Government Health Directorates [ETM/47], by Diabetes UK [10/0004010] and by in-kind contributions from the Scottish Diabetes Research Network. Genotyping was supported by the Juvenile Diabetes Research Fund [17-2013-7]. Generation Scotland received core support from the Chief Scientist Office of the Scottish Government Health Directorates [CZD/16/6] and the Scottish Funding Council [HR03006]. The development of the GENOSCORES platform was supported by a Springboard Award [SBF006/1109] from the Academy of Medical Sciences, supported in turn by the Wellcome Trust, the UK Government Department of Business, Energy and Industrial Strategy, the British Heart Foundation and Diabetes UK.

This repository contains summary-level data generated by performing Genomewide aggregated trans- effects (GATE) analysis in case-control study of Type 1 Diabetes (T1D).

Related Organizations

Leipzig University
Germany
University of Edinburgh
United Kingdom

Keywords

CTLA4, type 1 diabetes, expression quantitative trait loci

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