The experiment was conducted at the reaearch field of the Department of Crop Science and Technology, University of Rajshahi, Rajshahi-6205, during the Rabi season from November 2015 to April 2016 to study the effect of sulphur and boron on growth and yield performance of boro rice (cv. BRRI dhan28). The experimental area belongs to High Ganges River Floodplain under Agro Ecological Zone-11 (AEZ-11). The experiment was constructed with two factors viz., factor A (sulphur) and factor B (boron) with three level of doses of each, i.e., S0: without sulphur (control), S1: 20 kg S ha-1, S2: 30 kg S ha-1, and B0: without boron (control), B1: 2 kg B ha-1, B2: 3 kg B ha-1. The experiment was conducted in a Randomized Complete Block Design (RCBD) with three replications. The results revealed that S and B significantly influenced the growth, yield contributing traits and yield of rice, and the treatment of S1B1 (20 kg S ha-1 with 2 kg B ha-1) performed the best results of number of tillers hill-1 (28.78), panicle length (26.94 cm), grains panicle-1 (177.57), filled grains panicle-1 (150.27), 1000-grain weight (29.75 g), highest grain (6.30 t ha-1), straw (5.91 t ha-1), and biological yield (12.21 t ha-1) and HI (51.60%). So, it can be suggested to apply S at 20 kg ha-1 and B at 2 kg ha-1 with recommended dose of NPK and Zn for maximum yield of boro rice in calcareous soils of AEZ-11.