In the Molten Salt Fast Reactor (MSFR), fuel is dissolved in a liquid salt, causing the formation and decay of fission products, such as noble metals, inside the salt. Noble metals have very low solubility and do not dissolve in the salt. They are known to agglomerate into particles which, in turn, diffuse, drift or sediment to interfaces such as walls, free surfaces and bubbles, where they deposit. Leveraging this in the MSFR, online or offline helium bubbling is foreseen to act as a means to extract noble metal particles from the salt. This can potentially limit strong deposition of particles onto walls (i.e., plating), preventing dangerous decay heat hotspots in the heat exchangers or other primary circuit components. In this paper, we investigate the efficiency of particle removal by helium bubbles in the MSFR using CFD modelling. Theoretical estimates of equilibrium particle size distributions are used as initial condition. CFD calculations are performed in a simplified MSFR geometry. Bubble expansion, turbulent bubble coalescence and turbulent break-up are accounted for using the poly-disperse LogMoM model [1], embedded in the two-fluid framework in OpenFOAM. The CFD analyses presented in this paper, in conjunction with the developed theory of noble metal particle formation, growth and capture, will help in the understanding and optimization of the fuel cycle in the MSFR or any other molten salt reactor design. The precise knowledge of how noble metal particle populations in the salt can be controlled, and how plating of noble metal particles onto primary circuit reactor components can be reduced, contributes to safe molten salt reactor operation.