Supporting data for "Dissecting the cellular architecture of neuroblastoma bone marrow metastasis using single-cell transcriptomics and epigenomics unravels the role of monocytes at the metastatic niche"

Authors: Fetahu, Irfete S.; Esser-Skala, Wolfgang; Dnyansagar, Rohit; Sindelar, Samuel; Rifatbegovic, Fikret; Bileck, Andrea; Skos, Lukas; +15 Authors

doi: 10.5281/zenodo.8070469 , 10.5281/zenodo.7707614 , 10.5281/zenodo.7707613

Supporting data for "Dissecting the cellular architecture of neuroblastoma bone marrow metastasis using single-cell transcriptomics and epigenomics unravels the role of monocytes at the metastatic niche"

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Abstract

This data repository contains several datasets supplementing the paper “Dissecting the cellular architecture of neuroblastoma bone marrow metastasis using single-cell transcriptomics and epigenomics unravels the role of monocytes at the metastatic niche” by Fetahu, Esser-Skala, Dnyansagar et al. (2023). HOMER_Results.zip: detailed results of the HOMER analysis nblast_scopen_gene_activity_normalized_motifs_added.rds: Seurat object with scATAC-seq data snp_array.tgz: SNP array data R_data_generated.tgz: Files generated by the scRNA-seq analysis scripts in the GitHub repository associated with the publication.

This study was funded by the Vienna Science and Technology Fund (WWTF#LS18-111, to S.T.M., N.F., and R.L.), MAPMET (FWF#P35841-B, to S.T.M.) by the Austrian Science Fund and LIQUIDHOPE (FWF#I4162, to S.T.M.) by the Transcan-2/ERA-NET initiative, EPICODE (FWF#P35072 to I.S.F.) by the Austrian Science Fund grant, and the St. Anna Kinderkrebsforschung e.V.

Related Organizations

St. Anna Children's Cancer Research Institute
Austria
University of Vienna
Austria
University of Salzburg
Austria
Medical University of Vienna
Austria

Keywords

neuroblastoma, bone marrow, scRNA-seq, metastasis, scATAC-seq, heterogeneity, monocytes, microenvironment, single cell

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