{"references": ["Cole, G., Prendergast, R., Henney, O. (1973). In vitro correlates of lymphocytic choriomeningitis (LGm) virus-induced immune response. In: Lymphocytic Choriomeningitis virus and Other Adeno-viruses. Springer-Verland, New York, p. 61.", "Dimov, V., Slavcheva, S., Toshkov, A., Trifonova, Sv., Hadjiivanova, N. (1990). Immunosupression after experimental infection with bovine rhinotracheitis virus. Acta Microbiol. bulg. 251, 46\u201353.", "Ellis, J., Davis, V., 'I'ales, L., Pratt, D. (1990). Clinical and immunological response of cattle to administration of a vaccine containing modified-live bovine respiratory syncytial virus. JAVbMA 196, 4, 583\u2013589.", "Field, E., Smith, M. (1984). Cell-mediated immune response in cattle to bovine respiratory syncytial virus. Am J 7et Res. 45, 8, 1641\u20131643.", "Kumagai, D., Ogra, P. (1985). Development of cell-mediated cytotoxic activity in the respiratory tract after experimental infection with respiratory syncytial virus. J Ixp Immunol. 61, 351\u2013359.", "Larsen, L. (2000). Bovine respiratory syncytial virus (BRSV): a review. Acta Vet Scand. 41, 1, 1\u201324.", "Lehmkuhl, H., Gough, P. (1977). Investigation of causative agents of bovine respiratory tract dis-ease in a beef cow- calf herd with an early weaning program. Am J Vet Res. 38, 1717\u20131720.", "Nash, A., Dalziel R., Fitzgerald J. (2015). Recovery from Infection. Mims' Pathogenesis of Infectious Disease. 233\u2013255", "Schmidt, U, Beyer J, Polster U, Gershwin L., Buchholz U. (2002). Mucosal immunization with live recombinant bovine respiratory syncytial virus (BRSV) and recombinant BRSV lacking the envelope glycoprotein G protects against challenge with wild-type BRSV. J Virol., 76, 23, 12355\u201312359.", "Schmidt, M., Varga, S. (2018). The CD8 T cell response to respiratory virus infections. Frontiers in immunology, 678.", "Sharma, R., Woldehiwet, Z. (1991). Cytotoxic T-cell response in lambs experimentally infected with bovine respiratory syncytial virus. Vet Immunol and Immunopath. 26, 237\u2013246.", "Sharma, R., Woldehiwet, Z. (1992). Reinfection of lambs with bovine respiratory syncytial virus. Res Vet Sci. 52, 72\u201377.", "Smith, M., Frey, M., Dierks, R. (1975). Isolation, characterization and pathogenicity studies of a bovine respiratory syncytial virus. Arch Virol. 47, 237\u2013247."]}

Lambs inoculated intratracheally (IT) and subcutaneously (SC) with bovine respiratory syncytial virus (BRSV) vaccine were evaluated for development of cell-mediated immune (CMI). Cytotoxic T-cell response showed better immune response in lambs, vaccinated IT. Cytotoxic activity of lambs immunized IT and SC with BRSV and neutralizing antibody values were investigated dynamically.