NEANIAS is an EU project that co-designs, develops and deliver innovative thematic services for European Open Science Cloud (EOSC) communities in three major sectors: Underwater research, Atmospheric research and Space research. NEANIAS aims to maximize the industry/research engagement by identifying and addressing all the challenges ensuring thus the sustainability of the services in question. These challenges are stemming not only from the funding needs but also from requirements of EOSC, the availability of data, the need for a common governance as well as from security and privacy related issues. This white paper is based on the lessons learnt and the experiences gathered during the project. It describes the best practices for sustainable services on EOSC which could be a useful tool for all the stakeholders of the EOSC ecosystem.