Human activities place additional pressure on the limited water resources in arid and semi-arid areas, and the overexploitation of groundwater threatens its quality and sustainability. Non-conventional water represents an alternative and extra resource in this situation. Reuse and recycling the treated wastewater reduce the pollution and protect the groundwater resources against pollution and reinforce their sustainability. Textile industry produce and release wastewater near rivers in the Grombalia case study site (Tunisia), which is characterized by high levels of organic, inorganic materials and dyes residues. Innovative scenarios based on the anodic oxidation of textile effluents are developed in the current study. The findings of treated wastewater quality, treatment costs, and related environmental impacts are contrasted with those of in situ treatment (a reference scenario). The effectiveness of electrochemical technology is related to the simultaneous oxidation and reduction on bipolar BDD electrodes. Three optimized treatment scenarios are proposed to improve the real-world applicability of the sustainable treatment. The best solution is the anodic oxidation post-treatment which was selected based on pollution removal and economic costs. Eco-efficiency results confirmed this choice in terms of environmental benefits which are quantified by COD removal enhancement and water reuse potential.Keywords: groundwater pollution, textile industry, anodic oxidation, eco efficiency, Reuse.Acknowledgment“This paper is supported by the PRIMA program under grant agreement No1923, project InTheMED.. The PRIMA program is supported by the European Union”.