Gonorrhea is a sexually transmitted infection caused by Niesseria gonorrhoeae. According to the World Health Organization (WHO), there are around 30.6 million cases of gonorrhea globally, with approximately 4000 babies blinded each year as a result of untreated maternal gonococci infections. Although it can be effectively treated. It can lead to significant consequences in certain people, including pelvic inflammatory disease in women and epididymitis in males. The treatment of gonorrhea is largely based on oral or injectable third-generation cephalosporins like cefixime and ceftriaxone, but concerns have recently been raised as to their continuing adequacy in the condition, as well as the rise of diminished resistance to azithromycin, which has improved the control of gonococcal infections. Medicinal plants have been used for centuries in the management of various diseases. They are cheaper and have relatively lesser adverse effects. This review is aimed at giving an exposition on the use of medicinal plants in the treatment of gonorrhea with the different species of flowering plants which are used for the treatment of gonorrhea. The etiology, clinical manifestations, epidemiology, and effective remedies from medicinal plants are discussed in this review