The present work examines the experimental data on the changes in glucose level in the blood of rabbits of different ages after dereceptation of olfactory analyzer, keeping them in the constant illumination /darkness regimes for 10 days and under interomechanoreceptive stimulation (stimulation of rectal receptors at pressure of 80-100 mm. m.c.). In the course of the investigation it was revealed that disturbance of olfactory function caused decreasing in the blood glucose level and the degree of the change depended on the animals’ ages. Long-term illumination or darkness regimes insert a definite correction in the rhythmic regulation of glycemic reaction in the blood at both in sensory deprivation and in interoreceptive stimulation.