Vitiation of Agni in Amashaya (stomach) region due to various reasons causes Amlapitta. Some of the common Pitta vitiating factors are fasting, eating between meals, worry, hurry, spicy foods etc. These factors derange the Pachaka Pitta (digestive enzymes etc.) and as a result Pachaka pitta vitiates. Thus developed condition is called Amlapitta. Hydrochloric acid (HCl) when not utilized well, or when produced in large quantity in the stomach region causes inflammation of stomach (gastric = related to stomach), that is called gastritis. This can derange the digestive procedures. The increased or normal level of HCl can destroy the soft tissue (epithelium) lining of esophagus, stomach, duodenum etc. If not managed on time this can give rise to ulceration (breech in tissue).Usually the esophageal sphincter muscle contracts thus preventing the stomach acid from shooting up into the esophagus, but if this muscle are not functioning properly, the acid can slip past it and this is when heartburn symptoms start, which is called Gastroesophageal reflux. Due to lifestyle changes and changes in food habits people are mainly suffering from GIT disorders. Amlapitta among them is a most commonly seen disease. This article is a case study of a 40 years male patient with signs & symptoms of Urdhwaga Amlapitta. Patient was treated with ayurvedic medicine and principles of Ayurveda according to Rogavastha and Doshavastha. This case study shows potential of ayurveda and it proves ayurveda has evidence based treatment. In this case study patient of Urdhwaga Amlapitta was treated with Shamana Aushadhi according to his Prakruti, Dosha, Dhatu and Mala. Rapid but steady improvement in patient’s complaints.