The use of artificial insemination in pigs has been adapted worldwide as the reproductive method of election at farm level. The postcervical method is launch as a method to improve the reproductive efficiency and genetic progress. A strategy to enhance farrowing rate and litter size of artificially inseminated female pigs is to “stimulate” the uterus and oviduct by adding various compounds to extended boar semen or injecting a compound into the female before insemination. The aim of this study was to evaluate the effect of seminal synthetic plasma Predil MR-A® as a method to facilitate procedures with postcervical artificial insemination of sows. The postcervical insemination was performed with 1.5 x 109 spermatozoa in control group and 1.5 x 109 spermatozoa with 20 ml of chemical synthetic plasma Predil MR-A® in test group. The results show that after postcervical insemination with in combination of chemical synthetic plasma Predil MR-A® were obtained 84,27 % conception rate, 83,15 % farrowing rate, 10,79 total born piglets and 10.07 piglets born alive per liter.