The spreadsheet contains the HPLC integration peaks monitoring the photolytic and photocatalytic degradation of the antibiotic ciprofloxacin (CIP) in milliQ water. The initial concentration of CIP is 10 mg/L. In the spreadsheets is shown the obtainment of 1st order kinetic constant rates for different photoreactor designs using 2, 3, 4 or 6 UVA-LED strips around the reactor, distanced 10 or 15 mm from the reactor's walls. The influence of different controlled periodic illumination's duty cycle (0.50 and 0.75) is also shown. Calculations of EEO (electrical energy per order consumption) are also made for each reactor set up. The irradiance values for each photoreactor design calculated by an optical software is presented as planar projections of the cylindrical reactor. Images showing the radiant flux in the photoreactor's middle cross section obtained by the software are also shown Finally, a full factorial design of experiments is made to obtain a model of prediction of kinetic constant rates and EEO values. Predicted vs experimental values are plotted.