The study aimed to investigate Career Aspirations among Graduate Students in Vellore District. The questionnaire was used for data collection from 739 graduate students by using multi-state sampling method with three different colleges namely Government, Aided and Self–finance colleges affiliated Thiruvalluvar University in Vellore District. The research adopted descriptive design. The data were analyzed using the descriptive statistics from the Statistical Package for Social Scientist (SPSS 20 version). The study has found that there is association between students" career aspiration and by their gender, stay place (Domicile), course of studying, academic performance, motivational persons for their career decisions. The graduate students are a crucial human resource for promoting the development of a country. They are also the movers of change in the socio-economic and technological innovation. Present graduate students have strong desire to achieve something high or great. The career aspirations include, Teaching, Any good jobs (govt. or private), Business, Administrative, Technical, Defense & security and Legal services. The study used various statistical methods such as; chi-square test, t-test and ANOVA test. The various suggestions given here would certainly help the graduate students, parents, teachers and educational institutions join hands to provide clear career guidance, motivation to choose better career towards their successful life.