This workbook contains the raw data acquired from the sampling of cores and water collected at 1,800 m depth in the NEOM Brine Pool, Gulf of Aqaba. The file captures the geochronology of the long core (S1-S2), X-ray fluorescence scanning (S3), X-ray diffraction (S4), geochemical analyses of the core sediments and overlying bine, plus associated uncertainties, and measurement precision (S5), and genomics (S6).