In line with the vision of the SeeRRI project: establishing a foundation for building self-sustaining research and innovation ecosystems in Europe through Responsible Research and Innovation (RRI), the present Deliverable 2.2 ��� Report on R&I ecosystem mapping of the territories from a comparative perspective constitutes an essential step in the establishment of a conceptual and theoretical foundation for self-sustaining R&I ecosystems. The results of the mapping will provide an important impetus for subsequent work packages, in particular, to the interactive stakeholder processes within and across the regions. The results are also intended to pave the way for the development of a generalized empirical framework that can be used to characterize territorial R&I ecosystems in the future. The empirical analysis has been accomplished following the guidelines to implement a comprehensive mapping of R&I ecosystems, as outlined in Deliverable 2.1 ��� Report on procedures and guidelines for active mapping. The aim of this report is to present the results of the systematic quantitative mapping of the three territorial R&I ecosystems selected as cases in SeeRRI ��� Nordland, Lower Austria, and B30 ��� in terms of (i) their R&I actors of different organizational types, (ii) being engaged in R&I activities of different forms, and (iii) the actors��� R&D collaborations and their engagement in regional, national and international networks.