The first meeting for the FNR-16-2020 Cluster “Enzymes for greener products”, organised in cooperation with the European Research Executive Agency (REA) (Unit B3 “Biodiversity, Circular Economy and Environment”), was held online on 14th October 2021. This Cluster gathered together to join efforts for a higher efficiency and impact of the 4 integrating projects: EnXylaScope (Grant Agreement no 101000831), FuturEnzyme (Grant Agreement no 101000327), OXIPRO (Grant Agreement no 101000607) and RADICALZ (Grant Agreement no 101000560). These projects are funded under the frame of Horizon 2020 Work Programme 2018-2020, call “Food and Natural Resources”, topic FNR-16-2020 “Enzymes for more environment-friendly consumer products”. This meeting is the first of a series of meetings through which the 4 Consortia, in accordance with the terms of the Grant Agreement, will undertake the best collaborative efforts with a view to maximise efficiency and impact, by favouring synergies and avoiding overlapping or duplication of activities. This is especially important given that the 4 projects target multiple types of audiences such as scientific community and other social audience, SMEs, industry, consumers, policy makers, etc. The Project Coordinators and Project Managers of the 4 projects attended the meeting, which was joined by the 2 Project Officers and the Head of Sector in Unit B3 “Biodiversity, Circular Economy and Environment” of the European Research Executive Agency (REA), to give advice and help identifying synergies. The Policy Officer of the European Commission Directorate-General “Research and Innovation” also presented the policy aspects related to the topic FNR-16-2020. This meetup was proposed by Gro Bjerga, Coordinator of OXIPRO, and Manuel Ferrer, Coordinator of FuturEnzyme, and soon accepted by the rest of the Coordinators, at which the Project Officers agreed. It was organised by Spanish National Research Council CSIC, using the online platform Conecta CSIC. In here, the presentations are available.