This dataset contains skin conductance responses (SCR), electrocardyogram (ECG), respiration, electromygram (EMG), pupil size (PSR), and gaze coordinates measurements for 28 healthy unmedicated participants (21 females and 7 males aged 27.3 +/- 5.0) participating in a Pavlovian differential trace fear conditioning experiment with 2 sessions. CSs were isoluminant colored triangles presented on the screen center with grey background. US was a train of 83 square electric pulses with 0.2 ms duration with a duty cycle of 1.67%, delivered with a constant current stimulator on participants' dominant forearm through a pin-cathod/ring-anode configuration. SOA between the CS onset and US was 17 s. Participants underwent the conditioning task with CSs (CS+ 100% reinforced) and US delivery in session 1 with 4 blocks, and were tested in a retention/extinction task one week later in session 2 with 3 blocks, with CS and auditory startle probe (ST) delivered 15 s after CS onset via headphones (ca. 102 dB, 50 ms duration). No US was delivered during session 2. The ITI was jittered on each trial to be 30 +/- 2 s. During ITI, an attention task was performed with 14 sub-trials. The blocks in each session were recorded on the same day with self-paced breaks.

This work was supported by the Clinical Research Priority Program of the University of Zurich for the CRPP "Synapse & Trauma".