Present work involves analysis and optimization of the process parameters (like helium flow rate, pressure and temp.) for main components as (eight different heat exchangers as well as three different turbo-expanders) of helium liquefaction plant of refrigeration capacity 1 kW at 4.5 K. Nevertheless, this plant can be operated in mixed mode also as helium refrigerator-cum-liquefier, although it is optimized for refrigeration load. To optimize process of any helium refrigeration/liquefaction system, this is important to consider one independent variable at a time and under valid assumptions, and its effect on the various process. From the analysis, the optimized value of the concerned and considered process variables is taken. The main components of system that affect process parameters are compressor, heat exchangers ,expansion devices or expansion valve besides this basically concerned with the parameters of the heat exchangers as well as expansion engines. Current calculation work mainly total compressor mass flow rate, fraction of total compressor flow of mass diverted towards engines, inlet temperature to many expansion engine and heat exchangers are calculated and accumulated using steady state condition. Present study, analysis and optimization of the important operating parameters is done considering logical assumptions and fulfilling important practical constraints that are explained in this report.