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Codes for "Most synonymous mutations in yeast are strongly non-neutral"

Name: Codes for "Most synonymous mutations in yeast are strongly non-neutral"
Keywords: 2. Zero hunger

integration_instructionsResearch softwarekeyboard_double_arrow_right Software 27 Jan 2022Publisher:Zenodo

Authors: Xukang Shen; Siliang Song; Li, Chuan; Jianzhi Zhang;

doi: 10.5281/zenodo.5908478 , 10.5281/zenodo.5908477

Codes for "Most synonymous mutations in yeast are strongly non-neutral"

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Abstract

Codes for the article "Most synonymous mutations in yeast are strongly non-neutral" All_fitness_values_of_genes.tar.gz: The folder contains fitness data of 19 genes in four environments, separated by genes. All_mutations_four_env_SNF6_two_replicates-fitness.csv: A merged table contains all fitness data of 19 genes in four environments. Fitness_simulation.ipynb: Simulations to show that fitness estimates are the same (1) when strains are grown together and (2) when strains are grown individually. The simulation is to respond to a reviewer's question. dNdS-Nenv_curve.ipynb: Simulation of the impact of environmental changes on dN/dS. empirical_dNdS.ipynb: Calculation of expected dN/dS in the four environments.

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