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Parenchyma leukocyte infiltration is characterized by physical, chemical and bacteriological changes in the glandular tissue of the udder. Also that have affect on the quality and quantity of milk, too. Somatic cell count is a useful predictor of intramammary infection. Ductus papillaris is first defense line of udder. The aim of experiment was to determine relation between ductus papillaris length, somatic cell count and leukocyte infiltration in mammary gland parenchyma. During three years, 26 dairy cows were excluded from production and send to slaughterhouse. A week before sending cows to slaughterhouse, milk samples were took to determine somatic cell count. Udders from slaughtered cows were taken for measuring ductus papillaris length and for histopathology. From 104 mammary glands, 36 (52,94%) glands were with length of ductus papillaris less 5 mm, with parenchyma leukocyte infiltration between 50-75% and with milk somatic cell count above 400.000/ ml. According to statistical correlation test, show positive correlation between ductus papillaris length, leukocyte infiltration in parenchyma and somatic cell count. Also, to statistical test ANOVA, all results are less 0.05 that means there is a statistically significant difference between leukocyte infiltration and milk somatic cell count.