Obesity is a penalty of the modern era, the world-wide latest report on prevalence of obesity according to W.H.O states that around 250 million cases of obesity are being reported every year. Obesity is considered the most sedentary disorder which has been ranked as the fifth foremost reason for death globally. It is an increasing problem in the developed world and has substantial health effects. In Ayurveda obesity has been described as Medoroga. Acharya charaka mentioned that a person in whom excessive and abnormal increase of fat tissue (meda dhatu) along with mamsa dhatu is found which results in to pendulous appearance of buttocks, belly and breasts and whose increase bulk is not matched by a corresponding increase in energy is called Sthula purusha. There are many Medohardravays mentioned in Bhavprakash Nighantu. Bhavmisra, the author of Bhavprakasha Nighantu which is among one of the treatises in laghutrayi.This present study will be designed to screen the drugs having medohar action mentioned. Bhavaprakash Nighantu on the basis of their rasa, guna, veerya, vipaka and their corresponding actions/karma mentioned.Thisstudy illustrates the drugs which having medohar karma/action described are taken into consideration.