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Assessment of welfare and stress of cows at farms is a priority task for all involved in the milk production. The aim of this study was to investigate the effect of the level of welfare on the farm and metabolic adaptations in cows in early lactation on milk production and length of service period, the risk for the occurrence of below-average productivity of cows and benefits while eliminating stressful on the farm. Milk production and service period as most important productive characteristics of cows are dependent on welfare score of farm (principle of good health and good feeding) and metabolic adaptation of cows. Low welfare score and poor metabolic adaptation in early lactation showed additive effect in reducting of productive characteristics. Risk for decrease of productivity in cows exposed to low welfare score on farm and metabolic stress is higher then 1.9 to 2.8 time compared to cows that did not suffer from same stressors. Reduction of stressors by preventive inspection of locomotion system and hoof corection, determination of metabolic status using a metabolic profile and suplementation with energetics and antioxidans give the best balance of cost and benefit when used together.