The report “Effects of air Temperature on Cardiopulmonary Mortality and Morbidity in Europe” was prepared as a milestone of the EU Project EXHAUSTION. It summarizes the evidence on the effects of different levels and changes in ambient air temperature on cardiopulmonary (CPD) mortality and morbidity across Europe and puts a spotlight on the vulnerable and susceptible population. It can help stakeholders and policymakers to plan adaptation measures to protect the vulnerable and susceptible population and increase European resilience towards climate change and extreme weather events.