The current preliminary study concerns the identification of the effects human-humanoid interaction can have on human emotional states and behaviors, through physical interaction. Thus, we have used three cases where people face three different types of physical interaction with a neutral person, Nadine social robot, and the person on which Nadine was modeled, Professor Nadia Thalmann. To support our research, we have used EEG recordings to capture the physiological signals derived from the brain during each interaction, audio recordings to compare speech features, and a questionnaire to provide psychometric data that can complement the above. Our results mainly showed the existence of frontal theta oscillations while interacting with the humanoid that probably shows the higher cognitive effort of the participants, as well as differences in the occipital area of the brain and thus, the visual attention mechanisms. The level of concentration and motivation of participants while interacting with the robot were higher indicating an also higher amount of interest. The outcome of this experiment can broaden the field of human-robot interaction, leading to more efficient, meaningful, and natural human-robot interaction.