This dataset contains genome-wide association summary statistics for waist-to-hip ratio (WHR), as well as those for body principal components (PCs). A subset of 387,139 unrelated, white British individuals were analyzed for WHR. PCs were combined from the summary statistics for WHR and 13 other anthropometric traits (body mass index, standing height, weight, hip circumference, waist circumference, arm lean mass (left), arm fat mass (left), leg lean mass (left), leg fat mass (left), trunk lean mass, trunk fat mass, body fat percentage, basal metabolic rate) provided by the Neale lab (http://www.nealelab.is/uk-biobank). All traits were inverse-rank normal transformed (by the Neale lab or ourselves for WHR). All effect sizes, including those for PCs, are standardized, i.e. they represent the effects on a trait with variance 1.

{"references": ["Sulc, Jonathan et al. (2021) Composite trait Mendelian Randomization reveals distinct metabolic and lifestyle consequences of differences in body shape medRxiv 2020.09.03.20187567"]}