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4D Printing to fabricate an in vitro model of the pancreatic acino ductal unit

descriptionPublicationkeyboard_double_arrow_right Conference object 01 Jan 2020 Italy Publisher:Zenodo

Authors: Sgarminato, Viola; Tonda-Turo Chiara; Ciardelli Gianluca;

doi: 10.5281/zenodo.4781361 , 10.5281/zenodo.4781362

handle: 11583/2988248

4D Printing to fabricate an in vitro model of the pancreatic acino ductal unit

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Abstract

This project aims at reproducing the morphology and the composition of the pancreatic acino-ductal unit. More specifically, this work involves the use of a 4D printing system that combines melt electrospinning technology with an automatized layer-by-layer surface functionalization which provides biological cues to the surface of the melt electrospun structure. This 3D exocrine glandular tissue model mimics in vitro the physiological structure experienced by cells in vivo and serves as a powerful tool to investigate pathological processes such as the Pancreatic Ductal Adenocarcinoma (PDAC)

https://youtu.be/jn_5ZNTQ-AU

Country

Italy

Related Organizations

Politecnico di Torino
Italy
Polytechnic University of Turin
Italy

Keywords

Melt electrospinning, Pancreatic tumor, 4D printing, 4D printing, Melt electrospinning, Pancreatic tumor.

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