The experiment was conducted in the Agronomy Field, Sher-e-Bangla Agricultural University (SAU), Dhaka-1207 during the period of November 17, 2016 to March 29, 2017 on growth and yield performance of selected wheat genotypes at variable irrigation. In this experiment, the treatment consisted of three varieties viz. V1 = BARI Gom 26, V2 = BARI Gom 28, V3 = BARI Gom 30, and four different irrigations viz. I0 = No Irrigation throughout the growing season, I1 = One irrigation (Irrigate at CRI stage), I2= Two irrigation (Irrigate at CRI and grain filling), I3= Three irrigation (irrigate at CRI, booting and grain filling stages). The experiment was laid out in two factors split plot with three replications. The collected data were statistically analyzed for evaluation of the treatment effect. Results showed that a significant variation among the treatments in respect majority of the observed parameters. Results showed significant variation in almost every parameter of treatments. The highest Plant height, number of effective tillers hill-1, spike length, number of grain spike-1 was obtained from BARI Gom-30. The highest grain weight hectare-1 (3.44 ton) was found from wheat variety BARI Gom-30. All parameters of wheat showed statistically significant variation due to variation of irrigation. The maximum value of growth, yield contributing characters, seed yield was observed with three irrigation (irrigate at CRI, booting and grain filling stages). The interaction between different levels of variety and irrigation was significantly influenced on almost all growth and yield contributing characters, seed yield. The highest yield (3.99 t ha-1) was obtained from BARI Gom-30 with three irrigation (irrigate at CRI, booting and grain filling stages). The optimum growth and higher yield of wheat cv. BARI Gom-30 could be obtained by applying three irrigations at CRI, booting and grain filling stages.