The authors of the book have come to the conclusion that to improve the efficiency of managing economic systems it is necessary to use modern modern strategies, models and technologies. Basic research focuses on assessment the innovative potential of enterprise, analyzing the competitive environment, higher education and human resources, forming clusters. The research results have been implemented in the different models of environmental-economic management, implementation of financial innovations, mechanism for managing innovative development, digital transformation of the economy, introduction of Internet technologies, development of e-commerce, “business – education – science” triad, legal regulation of state aid and environmental taxation. The results of the study can be used in decision-making at the level of international business, ministries and departments that regulate the processes development of economic systems, ensuring stability and efficiency. The results can also be used by students and young scientists in developing of strategies, models and technologies for economic systems management in the context of international economic integration.