Observations of neutrino oscillations from the majority of experiments are consistent with a three-flavor framework. However, the excess of events seen by LSND and MiniBooNE may be incompatible with this model and, to explain these data using neutrino mixing, require an additional, sterile, neutrino. These intriguing results are inconclusive and are in tension with findings from other short- and long-baseline experiments. The NOvA experiment, which uses two functionally-identical liquid scintillator detectors over an 810 km baseline in the Fermilab NuMI beam, has the potential to set world-leading limits on parameters governing sterile neutrino oscillations by searching for a deficit of neutral current interactions compared to that predicted at the two detectors. The results of this analysis when applied to the full NOvA 12.3e20 POT antineutrino dataset will be presented and the first limits on the mixing parameters from long-baseline antineutrinos, will be shown.