This study aims to look for the effect of learning models and learning independence on higher order thinking skills in science learning of elementary school students. This research was conducted in class IV SDN Gandaria 3 Tangerang. The study design used an experimental method with treatment by level 2 x 2. Data analysis used 2-way variant analysis (ANOVA). The results of this study are (1) there are differences in high-level thinking skills of students who learn to use the 7E Learning Cycle Model with the Problem Based Learning Model. (2) There is an interaction between Learning Model and Learning Independence on the high level thinking skills of elementary school students. (3) high level thinking skills of students who have high Learning Independence using the Learning Cycle Model 7E higher than students who have high critical thinking skills who use Problem Based Learning Models. (4) high level thinking skills of students who have low Learning Independence who using the 7E Learning Cycle Model media is lower than students who have low critical thinking skills who use the Problem Based Learning Model.