Introduction Medical evidence suggests that contaminated hands are the main transmitters of disease. Hand washing is reflected as effective hygiene promotion activities for public health in the whole world. Aim This study aimed to determine the effectiveness of hand washing education on knowledge regarding hand washing and its importance among adolescence in selected schools. Materials and methods A quantitative research approach with Pre experimental one group pretest and posttest design was used to conduct the study in selected schools of Uttar Pradesh. Non probability purposive sampling technique was employed to select 40 adolescence. A self structured knowledge questionnaire containing 30 items were used for assessing the level of knowledge among the subjects. Data were analyzed using SPSS version 25. Results The mean score of the adolescence in pretest 10.2±4.1 is lesser than the mean score in posttest 20.2±4.3, t value 18.8 which is significant P = 0.001. There was an association found between the levels of knowledge among the adolescence with their mother’s education. Conclusion The study is concluded that hand washing education is effective to enhance knowledge among adolescence regarding hand washing and its importance. Attitude and practice of adolescence regarding hand washing also can be assessed in future studies. Bince Varghese | Shamil CB | Muskan Singh | Sumati Singh | Alka Pandey | Kamini Yadav | Rakhi Yadav | Rashmi Mishra "Effectiveness of Hand Washing Education on Knowledge among Adolescence Regarding Hand Washing and its Importance" Published in International Journal of Trend in Scientific Research and Development (ijtsrd), ISSN: 2456-6470, Volume-4 | Issue-3 , April 2020, URL: https://www.ijtsrd.com/papers/ijtsrd30601.pdf Paper Url :https://www.ijtsrd.com/medicine/nursing/30601/effectiveness-of-hand-washing-education-on-knowledge-among-adolescence-regarding-hand-washing-and-its-importance/bince-varghese