Gastritis is an inflammatory process in the gastric mucous and submucous in response to injury, which can be acute or chronic. Helicobacter pylori bacterial infection is the most common cause of chronic gastritis active throughout the world. The incidence of gastritis increases gradually because adiponectin levels decrease, this is because adiponectin protects the stomach from increased gastric acid through the anti-inflammatory effect of adiponectin. The purpose of this study was to determine the correlation between adiponectin and H. pylori gastritis and to find the relationship between adiponectin and nutritional status in H. pylori gastritis patients. In this study, there was difference adiponectinlevel between H. pylori infection, that hipoadiponectinemia has increased risk H. pylori infection. This study also found adiponectin serum was lower in higher body mass index and abdominal circumference.