This report describes the transdisciplinary framework for the UNISECO project and provides ‘structures’ to facilitate meaningful interactions for shared learning, synthesis, integration and co-construction of innovative, actionable knowledge for practical outcomes. Material has been drawn from resources of academia and practice, including the personal experience of the UNISECO consortium partners. This project has received funding from the European Union’s Horizon 2020 research and innovation programme under grant agreement N° 773901.