Giacinto Piero Tartaglia, Alessandro Annoni, Anders Frijs-Christensen, Fabrizio Bonato, Per Loekkemyhr and Giuseppe Merlo, European Commission, Joint Research Centre, Italy Horizon 2020 is taking a big step towards Open Science in Europe. The strategy for a smart, sustainable and inclusive economy underlines the central role of knowledge and innovation in generating growth and addressing the societal challenges of the century. The Communications COM (2012) 392 and 401, COM (2011) 833 and 882 and the C (2012) 4890, set out the action that the Commission is undertaking to improve access to scientific information and to boost the benefits of public investment in research increasing productivity, competitiveness and growth and detail scope and actions for implementation of the open access (OA) policies to the Member States. As a Commission body, in its focal role in providing scientific advice to policy making, the Joint Research Centre (JRC) must lead by example in providing OA to its publicly-funded research results, optimising the circulation, access to and transfer of scientific knowledge among key stakeholders in European research, such as universities, funding bodies, libraries, firms, governments and policy-makers, society at large. The actions undertaken by the JRC range from the implementation of OA policies to its participation in EU initiatives on how to foster OA, preserve scientific information, enhance the usefulness of scientific results in a pan-European knowledge-shared environment. The paper describes the JRC experience in implementing OA policy to scientific publications (in force since 1 January 2014), in implementing the Data Policy, adopted in 2014, for granting access to data, datasets, metadata, databases underpinning the scientific publications, and the online dissemination channels. As the JRC is the major resource of in-house models in the Commission, the paper presents its Modelling Inventory Database and Access Services, MIDAS, which allows users to identify suitable models for a particular purpose, to assess the use of these models for impact assessment, policy support and to access related datasets and documents. The paper also covers tools, e.g. the publication management system, PUBSY, establishing e-workflow and hosting features for ensuring high-quality peer-reviewed papers. The JRC extends the open concept to e-infrastructure (in a EU context) and to the opening of its high-quality large research infrastructure. Equally, the paper addresses the development of Open Science and the JRC initiatives to ensure a coherent understanding of the changing environment at political level. Giacinto Piero Tartaglia has been leading the Planning, Evaluation and Knowledge Management Unit since January 2014, in order to implement systems for comprehensive knowledge management at JRC, which might be extended to other areas in the Commission. As an MSc in Nuclear Engineering and Physics, PhD in Nuclear Science and Technology, Chartered Engineer, and a member of various professional associations, he has worked in several national and international organisations (e.g. ENEA, FZK, CEA, CERN), on thermo-fluid-dynamics, structural mechanics, nuclear engineering and physics, material properties, energy, before joining the JRC in 1987. He moved from applied research to management positions, responsible for complex and diversified projects/programmes, involving relevant resources, means and firms. In 1987, at the High Flux Reactor division (Petten), he was responsible for irradiation experiments (reactor materials, components) and radioisotopes production, ultimately managing the whole facility. In 1997, he moved to Ispra, where he was responsible for Advanced Materials and Technologies, and then Head of the Management Support Unit, and delegated overall coordinator, of the new Institute for Health and Consumer Protection. In 2002, he was Head of the Nuclear Decommissioning and Waste Management Unit, to eliminate historical liabilities from the site. In 2005, as Head of the Maintenance & Utilities Unit, he developed a strategic plan, upgrading installations, eliminating hazards, to achieve high energy efficiency (20-20-20 policy), thus minimising the site environmental impact.