This study aims to determine the practicality of integrated science teacher books integrated type with the theme of adaptation of the human body to temperature changes that are integrated with 21st-century learning. The method used is a plomp development model in which this model has 3 stages. The research is limited to the prototype stage. Data collection is done through interviews. The questions asked were about concept maps, materials, integration of lonsor land material, learning activities, and examples of assessments contained in the teachers book. According to the teacher, the concept map contained in the teachers book illustrates all the material to be studied. Teacher books produced and tested in the field obtained a valid and practical teachers book.