Biology learning contains of many abstract concepts, therefore teachers need media that can support a good learning process. Good learning media refer to a medium that can interpret complex concepts into simply concepts. Producing of process-image base learning material package need critical thinking skills. This study aimed to examine the effectiveness of the use of learning material packages of human being reproduction systems based on process images on students\' achievement and critical thinking skills. This study is a quasi-experimental by one group pretest-posttest design. This study is conducted in three high schools (A, B, C). The data of the study are score of students? achievement and critical thinking skills, where analyzed quantitative descriptive. Findings of research shows that students? achievement and critical thinking skilss in schools A and B in the medium category, and in school C in the high category.