Preparation of An Effective Antimicrobial Agent from Virgin Coconut Oil

Virgin coconut oil (VCO) was extracted from locally abundantly available coconut by cold press method. The physicochemical properties VCO were investigated. To synthesize potent antimicrobial agent (monoglycerides of MCFAs that rich in monolaurin), VCO was enzymatically hydrolyzed and MCFAs rich fraction was then separated. By using this fraction monoglycerides of MCFAs was prepared via enzymatic glycerolysis using RM IM immobilized lipase. The MICs of this glyceride were found to be <1.7 μg/mL against S. aureus and P. morganii.

Keywords

monolaurin, medium chain fatty acids, monoglyeride, antimicrobial agen

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