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Cold atmospheric pressure plasmas (CAP) have drawn much interest for biomedical applications in the last decade or so [1]–[3]. One of the most interesting applications is cancer treatment where CAP was used effectively in a wide number of different scenarios and in some cases it even exhibited selectivity in treating cancer while leaving the healthy tissue intact [4]–[6]. In this work a helium (both pure and with 1000 ppm O2 admixtures) plasma jet is generated in a capillary soda lime glass tube with internal diameter of 3 mm initiated by a 15 kHz, 50% duty cycle, 13 micro sec rise time, and positive 6.0 kV applied voltage. The plasma is used to treat (for 60s-240s) the cancerous line MCF-7F as shown in Figure 1. The results obtained demonstrate that plasma (He and with O2 admixtures) can be very effective (reducing viability as determined via flow cytometry) for this cell line. This project has received funding by the EU Horizon 2020 (MSCA-IF-2015) program under grant agreement 703497. References [1] M. Laroussi, IEEE Trans. Plasma Sci., 43, 703–712 (2015) [2] D. B. Graves, Phys. Plasmas, 21, 080901 (2014) [3] G. Fridman, G. Friedman, A. Gutsol, A. B. Shekhter, V. N. Vasilets, and A. Fridman, Plasma Process. Polym., 5, 503–533 (2008) [4] D. Yan, J. H. Sherman, and M. Keidar, Oncotarget, 8, 15977–15995 (2017) [5] D. B. Graves, Plasma Process. Polym., 11, 1120–1127 (2014) [6] M. Wang, B. Holmes, X. Cheng, W. Zhu, M. Keidar, and L. G. Zhang, PLoS One, 8, e73741 (2013)
International Workshop on Plasma for Cancer Treatment (IWPCT 2019), April 1-3, 2019 Antwerp, Belgium.
plasma treats cancer, plasma jet
plasma treats cancer, plasma jet
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