Analysis Of Runs Of Homozygosity In Local And Commercial Italian Pig Breeds

Authors: Giuseppina Schiavo; Francesca Bertolini; Claudia Geraci; Stefania Dall'olio; Leonardo Nanni Costa; Donato Matassino; Vincenzo Russo; +2 Authors

doi: 10.5281/zenodo.344819

Analysis Of Runs Of Homozygosity In Local And Commercial Italian Pig Breeds

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Abstract

Runs of homozygosity (ROH) are defined as continuos and uninterrupted chromosome regions in which all loci are homozygous in an individual, even if in the population these loci are not fixed for any allele. ROH are single nucleotide polymorphism (SNP)-derived metrics of autozygosity and provide a DNA based measure of the inbreeding level, as the two homozygous long DNA streches are considered identical by descent (IBD).

Related Organizations

Alma Mater Studiorum University of Bologna
Italy

Keywords

inbreeding, SNP, autozygosity, biodiversity

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