Background: Anemia is a common blood disorder that is defined by World Health Organization (WHO) as hemoglobin less than normal amounts. Anemia is a common accompaniment of diabetes. HbA1c is included in diagnostic criteria of diabetes mellitus. Diabetes can drop of the protein hemoglobin levels, Type 2 diabetes mellitus is a common metabolic disease that is increasing on daily basis. It gets worse over time leading several shot and long term complications. Objective: To determine the frequency of anemia in type 2 diabetes mellitus subjects. Study design: Cross-sectional study. Sample size: 424 male and female subjects known case diabetes mellitus. Place: PMCH Nawabshah. Duration: Jan 2016- Dec 2018. Inclusion criteria: all male female age 20-70 years subjects admitted in PMCH Nawabshah. Methodology: The study was carried out among the healthy control subjects and in diabetic subjects to evaluate of the elements of absolute RBC, WBC and platelets count as a risk factor for diabetes among the discrete male and female population of Nawabshah and associated areas in Pakistan. The non-diabetics served as controls for the study. Statistical data was obtained for the data. Results: anemia; decrease RBCs count and Decreased Hb levels were common finding in patients suffering from diabetes mellitus. Keywords: Anemia; Type 2 Diabetes Mellitus (T2DM); Complete Blood Count (CBC); HbA1C