International Conference on Heart Health in Developing Countries, 10-14 October 1999, New Delhi, India, by: All India Institute of Medical Sciences, Poster presentation, P:51 Abstract: Objective: This is an experimental study carried out in 1998 to evaluate the correlation between health education and the level of human serum lipids in hyperlipidic patients. Method: This study enroll 102 hyperlipidic individual (age group 28-77 years old, mean of cholesterol level= 263.3 mg/dl, Mean of the TG=376.05 mg/dl and mean of LDL=191.4 mg/dl) referred by Esfahan (Iran) GPs were selected as sample populations using random sampling method. The sample population was randomly divided into two groups of treatment (59 case and 43 control). Data was selected using a questionnaire and measuring the level of TG. Chol, LDL, HDL and weight indexes and BMI of the subjects.Attitude and practice were measured after collecting the questionnaire and measuring above parameters of both the treatment and control group, next the health education program was carried out for treatment group. Three months later the same procedures of data collection was carried out for both groups. Result: Our result indicated a positive effect of health education on the decreased of the following factors in the treatment group. After three months the levels of Chol, LDL, Weight Index and MBI were decreased significantly (p=0.000) using student t test. But there was no significant changes on the level of HDL (P=0.22). There was no significant changes on the levels of TG (P=0.58). Conclusion: Our study shows a strong correlation between the health education and treatment and control of hyperlipidemic patients and other risk factors of coronary heart disease.