Purpose: The aim of our research work was to choose the best available technology of using the alternative engine fuels in vehicle and tractor technique use. Methodology: The methodology of multicriterial optimization was adopted for the purpose of the research. Results: There are given the results of calculating researches related to the choice of the best available techniques of the alternative engine fuels in vehicle and tractor technique use by the method of complex evaluation of fuel and power indexes of alternative fuels and engine, ecological safety and economic feasibility of vehicle exploitation. Fuel and power indexes of the fuels and of the engine are estimated by the criterion of adaptation, which is calculated by the method of hierarchies, ecological safety is evaluated taking into consideration the number of pollutant emissions with exhaust gases, their maximum permissible concentrations and safety class, economic feasibility of technique exploitation is estimated by the economic feasibility criterion which is calculated taking into account the economy of exploitation charges while using alternative fuels and placement of funds for technique re-equipment. The highest value of general criterion of the choice of suitable technique of fuel use which integrates the listed criteria, belongs to the technique of natural gas using in the gas engine re-equipped from the diesel one, petrol diesel fuel has the lowest value. The theoretical contribution: is The research findings have contributed to the development of a common methodology of estimating the factors of vehicles functioning on alternative fuels on criteria of technical suitability, environmental safety and economic efficiency of operation. Practical implications: The proposed methodology allows to estimate the technique indexes while its functioning on different types of fuel by one general criterion, which simplifies a lot the choice of technique of rational type of fuel use.