Background: An Interventional study was conducted in Governmental Pediatric Hospitals in Khartoum State. Distribution of (169) nurses in five different hospitals is as follows (15%) from Gaffer Ibnaouf, (7 %) from Abdurrahman Al Mahdi, (44%) from Mohammed Alamein Hamed Pediatric Hospital, (17%) from Ahmed Gassim and (17%) from AlBulk pediatric hospital. This study is aimed to assess the impact of an educational program for nurses on how to manage pain in children. Methodology: Data was collected by interviewing candidates using questionnaires that covered objectives under study and Data was analyzed by using SPSS (Statistical package for social sciences) computer program. Results:The deficits in pain management can be improved by implementing pain education programs. Nurses scored low in having knowledge and attitudes towards pain prior to pain education; whereas, a significant improvement in their knowledge and attitude after the delivery of pain education was explicit. Conclusion: The deficits in pain management can be improved by implementing pain education programs.