CollEx-Persée is a research infrastructure set up in France in 2017. It brings together 19 research libraries, 4 national operators (Persée for digitisation; ABES for bibliographic data; CTLES for document conservation; INIST-CNRS for data mining) and the Bibliothèque nationale de France. It aims to facilitate access to and use of library collections by researchers in a context where the relationships between these two communities are being tested. Indeed, technical developments and the massive availability of online documentary resources have changed the research process. The majority of researchers in all disciplines have adapted to the direct accessibility of digital content from their computers, leading to a declining attendance of library buildings. CollEx-Persée’s vision is a library that develops hybrid collections (thinking together digital resources, print, research materials including archives and iconographic resources) backed by services that meet the new needs of researchers as users of information sources of all kinds and producers of data and research results. The originality of CollEx-Persée relies on the choice of a national network organization dedicated to research support and governed by university presidents, librarians and researchers. The members of the consortium identify and carry out various actions in common: digitisation programmes; collection mapping; concerted licensing of specific electronic resources; assistance with research data management; open science support; document delivery; shared conservation plans, etc. CollEx-Persée is funded by the French Ministry of Higher Education and Research. These human and financial resources allow for supporting structuring programmes, launch calls for projects and organise bibcamps and study days to bring communities together and share expertise. CollEx-Persée also aims to share vison and best practices with other similar European organizations during meetings (German-French seminar in Strasbourg in December 2017 with FIZ- Fach Informazions Dienste). LIBER would represent a perfect hub for this goal. The communication will first present the strategy for creating CollEx-Persée and the breakthroughs introduced by this new system, then its organization, networking activities and first achievements. We will focus on calls for projects that have made a very concrete contribution to bringing librarians and researchers closer together. Finally, we will present the emerging challenges, in particular the management of change within libraries and training for new professions.