Pathway Activation Strength (Pas) Analysis Of Microarray Data Reveal Similarities Of Aging With Age-Related Macular Degeneration And Hutchinson-Gilford Progeria ? Should Aging Be Considered As A Disease?

Aging is a complex multifactorial process leading to loss of function and age-related diseases. However, the contribution of aging to age-related diseases is still poorly understood. In this research study we compared differential tissue-specific pathway activation profiles in normal aging with progeria, Age-related Macular Degeneration (AMD). We discovered the age-related diseases share similarity with healthy aging at the signaling pathways level

Keywords

Aging, Hutchinson-Gilford progeria, Hutchinson-Gilford progeria , AMD

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