A business game as a pedagogical means of humanizing education and an active form of education, which allows maintaining a constantly high interest of students in learning, activates their independent activities and contributes to self-realization and self-affirmation in real situations is considered in this article. The purpose of the article is to analyze the place and role of the business game, as an active method of teaching, in revealing and confirming the humanistic tendencies of professional education. Analysis of recent research and publications allowed to identify and formulate the main provisions that determine the essence of the humanization of education. The implementation of these provisions required the search for new forms and methods of teaching and contributed to the development of innovative pedagogical technologies, one of which is business game as a form and method of training that simulates subject and social aspects of the content of professional activity. The practice of conducting business games at the Poltava University of Economics and Trade confirmed the need to use them in the educational process in order to form an adequate picture of future professional activities by consciously, purposefully assimilating students of educational material and the ability to use it to solve specific problems of the economy and production. As a result of the introduction of active teaching methods, it has been established that a business game contributes not only to the formation of specially oriented knowledge and skills, but also to personality development capable of self-realization, self-development, self-education, which is also a confirmation of the reality of humanistic tendencies in the educational process.