Oxy-fuel combustion in cement kilns is one of the capture technologies investigated in the CEMCAP Project. The present deliverable reports on optimization of a full-scale rotary kiln operating in oxy-fuel mode by using Computational Fluid Dynamics (CFD) and interaction with process simulation. An optimization procedure and a set of constraints have been defined and followed. The oxy-fuel flame is investigated at different input flow conditions at the burner and secondary gas stream from the clinker cooler, with the objective of reproducing a heat radiation profile to the clinker which is as close as possible to the BAT air reference case defined in CEMCAP. An acceptable trade-off has been found between kiln gas inlet conditions (composition and flow rates) and the boundary constraints imposed to the kiln in terms of hardware, process flow, and heat radiation to the clinker. The ThyssenKrupp designed POLFLAME burner has demonstrated to be able to generate an oxy-fuel flame with similar heat transfer characteristics in air and oxy-fuel requiring only to adapt the modulable swirl angle of the burner high velocity nozzles. Retrofit applications and air/oxy-fuel mode shifting are therefore possible without changing the burner. The study has shown the particular features of flame stabilization pattern with this burner and highlighted the rotary kiln characteristics that were most sensitive to the flame properties.