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This repository contains 218,578 unique image patches derived from histological images of colorectal cancer patients in the TCGA cohort (original whole slide SVS images are freely available at https://portal.gdc.cancer.gov/). All images in this repository are derived from snap-frozen tissue slides ("TS" or "BS" at the GDC data portal). Preprocessing All SVS slides were preprocessed as follows 1. automatic detection of tumor 2. resizing to 224 px x 224 px at a resolution of 0.5 µm/px 4. color normalization with the Macenko method (Macenko et al., 2009, http://wwwx.cs.unc.edu/~mn/sites/default/files/macenko2009.pdf) 5. assignment of patients to either "MSS" (microsatellite stable) or "MSIMUT" (microsatellite unstable or hypermutated) 6. randomization of patients to training and testing sets (~70% and ~30%). Randomization was done on a patient level rather than on a slide or tile level 7. equilibration of training sets by undersampling (removing excess tiles in MSS class in a random way) File description 1. STAD_TRAIN_MSS - training images (~70% of all patients) for gastric (stomach) cancer TCGA patients with MSS (microsatellite stable) tumors, 50285 unique image patches; FFPE samples 2. STAD_TRAIN_MSIMUT - training images ( (~70% of all patients) for gastric (stomach) cancer TCGA patients with MSI (microsatellite instable) or highly mutated tumors, 50285 unique image patches; FFPE samples 3. STAD_TEST_MSS - test images (~30% of all patients) for gastric (stomach) cancer TCGA patients with MSS (microsatellite stable) tumors, 90104 unique image patches; FFPE samples 4. STAD_TEST_MSIMUT - test images ( ~30% of all patients) for gastric (stomach) cancer TCGA patients with MSI (microsatellite instable) or highly mutated tumors, 27904 unique image patches; FFPE samples
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