Background:Bariatric surgery proved to be the only successful treatment option leading to long-term weight loss with improvement of obesity related comorbidities. The Laparoscopic Sleeve Gastrectomy (LSG) is now one of the most popular bariatric procedure worldwide with rising prevalence over last decade, while the Mini Gastric Bypass (MGB) is now gaining some popularity as a relatively new bariatric procedure Methods:The study involved forty patients; twenty of them had Laparoscopic Sleeve Gastrectomy (LSG), and twenty of them had Laparoscopic Mini Gastric Bypass (MGB). The patients were selected according to National Institute of Health (NIH) guidelines. All procedures were performed by the same team of experienced bariatric surgeons. all the patients had a one-year period of follow up after surgery and were evaluated for weight loss, morbidity (early, and late), impact on obesity associated diseases and effect on quality of life (QoL). Results:The two groups were matched considering the demographic data. Operative time was significantly longer in MGB group (P = 0.001), with mean operative time in MGB group was 74.75, while in LSG group was 53.25 min. One patient (5%) from LSG group developed stenosis and was managed by endoscopic balloon dilatation. Mean excess weight loss % after one year was 66.99% (? 1.739%) for LSG group and 67.76% (? 1.813%) for MGB group. The QoL after one year was varied between good and very good in both groups, with 70% of LSG group lie in very good category, and 75% of MGB group lie in the very good category. Conclusion:Both studied laparoscopic techniques; LSG and MGB were safe and effective, with similar results as regards significant weight loss and improvement of obesity-associated medical comorbidities and quality of life, with acceptable morbidity.